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Special therapeutic procedures

Liver resection is the only efficient therapeutic procedure for liver metastasis from colorectal carcinoma. It offers prolonged survival rates for patients who suffer such a spread disease. Unfortunately, only a small number of patients (75%) can receive this treatment when diagnosed. The number of metastasis and their location in both liver lobes determine the possibility of taking this treatment or not. For a very long period of time, these patients were considered unresectable, and therefore took palliative chemotherapeutic treatment.

In the last few years there has been important progress in the use of different chemotherapeutic treatments for this kind of tumors. This progress means partial response and, in unusual (o few) cases, full response. Thanks to the use of different medicines and protocols, 25% of patients with spread liver diseases -and even lung metastases- have been identified for surgery when diagnosed.

The combined work of oncologists and interventionist radiologists in our Department has made it possible to apply “individualized" modern therapy, answering to the very own characteristics of each patient and their illnesses. Thus, the aim is to fully eliminate the liver tumors at different stages and using different procedures (surgery, thermal ablation and chemotherapy). This formula represents the only therapeutic option that can be carried out nowadays with a healing intention.

Full surgical resection of lesions located in the liver lobe with less metastasis (or ablation with radiofrequency followed by chemotherapy for no less than 6 months) offers in many occasions a remarkable response that permits later on a total surgical resection of other areas of the liver. All this can be done with small functional and histological consequences for the liver, without increasing surgical morbimortality..

Clinical Cases: 
Clinical case 1
Clinical case 1

Multiple liver metastasis from colorectal carcinoma.

Chemotherapy.

Resection of metastasis located in segment I.
Preoperative portal embolization.
Chemotherapy.
Right liver resection extended to segment IV.
Resección hepática derecha ampliada al segmento IV

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