Prognostic Value of Lymph Node Status for Actual Long-Term Survival in Resected Pancreatic Cancer
Actual survival prognostic factors for resected R0 pancreatic cancer are not yet clearly defined. Furthermore, most of the papers focused on this topic are referred to actuarial survival (estimated but not real).
In our series of R0 resected pancreatic cancer with an actual survival greater than 5 years, the most powerful predictive factor was lymph node involvement, regardless of the number of metastatic nodes. This result underscores the importance of insisting on more powerful chemotherapy regimens or even postoperative radiotherapy regimens (if they did not receive it before surgery) in patients with positive nodes, even if there was only one, regardless of the total number of nodes affected, or the ratio between the number of positive nodes and the number of nodes resected in surgery (Lymph Node Ratio: LNR).